In Vitro pH Activity of Ibrexafungerp against Fluconazole-Susceptible and -Resistant Candida Isolates from Women with Vulvovaginal Candidiasis

The vaginal environment with candidiasis has a pH of 3.8 to 4.5 and this has a negative effect on the activity of antifungals. Ibrexafungerp was evaluated against 187 Candida isolates, including fluconazole-sensitive and -resistant Candida albicans, Candida glabrata, Candida krusei, Candida parapsil...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Sobel, Jack D., Borroto-Esoda, Katyna, Azie, Nkechi, Angulo, David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284466/
https://ncbi.nlm.nih.gov/pubmed/34001513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00562-21
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