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A Novel Running Wheel Mouse Model for Botulism and Its Use for the Evaluation of Postsymptom Antitoxin Efficacy

Antitoxin is currently the only approved therapy for botulinum intoxications. The efficacy of antitoxin preparations is evaluated in animals. However, while in practice antitoxin is administered to patients only after symptom onset, in most animal studies, it is tested in relation to time postintoxi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Schwartz, Arieh, Ben David, Alon, Hotoveli, Mordechai, Dor, Eyal, Diamant, Eran, Vivyorka, Arik, Rosen, Osnat, Torgeman, Amram, Zichel, Ran
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284437/
https://ncbi.nlm.nih.gov/pubmed/33972251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00421-21
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