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Role of Homologous Fc Fragment in the Potency and Efficacy of Anti-Botulinum Antibody Preparations

The only approved treatment for botulism relies on passive immunity which is mostly based on antibody preparations collected from hyper-immune horses. The IgG Fc fragment is commonly removed from these heterologous preparations to reduce the incidence of hyper-sensitivity reactions. New-generation t...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Torgeman, Amram, Ozeri, Eyal, Ben David, Alon, Diamant, Eran, Rosen, Osnat, Schwartz, Arieh, Barnea, Ada, Makovitzki, Arik, Mimran, Avishai, Zichel, Ran
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488030/
https://ncbi.nlm.nih.gov/pubmed/28555060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9060180
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