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Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins

Botulinum neurotoxins are bacterial proteins that cause botulism, a life-threatening disease. Therapy relies mostly on post-intoxication antibody treatment. The only accepted method to measure the potency of, and to approve, antitoxin preparations is the mouse lethality neutralization bioassay. Howe...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Rosen, Osnat, Ozeri, Eyal, Barnea, Ada, David, Alon Ben, Zichel, Ran
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5086636/
https://ncbi.nlm.nih.gov/pubmed/27669303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8100276
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