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A Novel Running Wheel Mouse Model for Botulism and Its Use for the Evaluation of Postsymptom Antitoxin Efficacy

Antitoxin is currently the only approved therapy for botulinum intoxications. The efficacy of antitoxin preparations is evaluated in animals. However, while in practice antitoxin is administered to patients only after symptom onset, in most animal studies, it is tested in relation to time postintoxi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Schwartz, Arieh, Ben David, Alon, Hotoveli, Mordechai, Dor, Eyal, Diamant, Eran, Vivyorka, Arik, Rosen, Osnat, Torgeman, Amram, Zichel, Ran
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284437/
https://ncbi.nlm.nih.gov/pubmed/33972251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00421-21
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