A Novel Running Wheel Mouse Model for Botulism and Its Use for the Evaluation of Postsymptom Antitoxin Efficacy

Antitoxin is currently the only approved therapy for botulinum intoxications. The efficacy of antitoxin preparations is evaluated in animals. However, while in practice antitoxin is administered to patients only after symptom onset, in most animal studies, it is tested in relation to time postintoxi...

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發表在:Antimicrob Agents Chemother
Main Authors: Schwartz, Arieh, Ben David, Alon, Hotoveli, Mordechai, Dor, Eyal, Diamant, Eran, Vivyorka, Arik, Rosen, Osnat, Torgeman, Amram, Zichel, Ran
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2021
主題:
Analytical Procedures
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284437/
https://ncbi.nlm.nih.gov/pubmed/33972251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00421-21
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