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Effects of a low-dose IL-2 treatment in HLA-B27 transgenic rat model of spondyloarthritis
ABSTRACT: INTRODUCTION/AIM: HLA-B27/human β2m transgenic rats (B27-rats) develop an inflammatory disorder resembling spondyloarthritis (SpA) with dysregulated IL-10/IL-17 production by regulatory T cells (Treg). Treg plays a major role in controlling pathogenic inflammatory processes. Interleukin 2...
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| Publicado no: | Arthritis Res Ther |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8283890/ https://ncbi.nlm.nih.gov/pubmed/34271972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02559-y |
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