Association of Monogenic and Polygenic Risk With the Prevalence of Open-Angle Glaucoma

IMPORTANCE: Early diagnosis of open-angle glaucoma can lead to vision-saving treatment, and genetic variation is an increasingly powerful indicator in disease risk stratification. OBJECTIVE: To compare polygenic and monogenic variants in risk of glaucoma. DESIGN, SETTING, AND PARTICIPANTS: Clinical...

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Bibliografski detalji
Izdano u:JAMA Ophthalmol
Glavni autori: Siggs, Owen M., Han, Xikun, Qassim, Ayub, Souzeau, Emmanuelle, Kuruvilla, Shilpa, Marshall, Henry N., Mullany, Sean, Mackey, David A., Hewitt, Alex W., Gharahkhani, Puya, MacGregor, Stuart, Craig, Jamie E.
Format: Artigo
Jezik:Inglês
Izdano: American Medical Association 2021
Teme:
Brief Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283675/
https://ncbi.nlm.nih.gov/pubmed/34264281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2021.2440
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