Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration

Primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD) are leading causes of irreversible blindness. Several loci have been mapped using genome-wide association studies. Until very recently, there was no recognized overlap in the genetic contribution to AMD and POAG. At genome...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cuellar-Partida, Gabriel, Craig, Jamie E., Burdon, Kathryn P., Wang, Jie Jin, Vote, Brendan J., Souzeau, Emmanuelle, McAllister, Ian L., Isaacs, Timothy, Lake, Stewart, Mackey, David A., Constable, Ian J., Mitchell, Paul, Hewitt, Alex W., MacGregor, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886254/
https://ncbi.nlm.nih.gov/pubmed/27241461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26885
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