Synaptic density in carriers of C9orf72 mutations: a [(11)C]UCB‐J PET study

Synaptic loss is an early and clinically relevant feature of many neurodegenerative diseases. Here we assess three adults at risk of frontotemporal dementia from C9orf72 mutation, using [(11)C]UCB‐J PET to quantify synaptic density in comparison with 19 healthy controls and one symptomatic patient w...

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Publicado en:Ann Clin Transl Neurol
Autores principales: Malpetti, Maura, Holland, Negin, Jones, P. Simon, Ye, Rong, Cope, Thomas E., Fryer, Tim D., Hong, Young T., Savulich, George, Rittman, Timothy, Passamonti, Luca, Mak, Elijah, Aigbirhio, Franklin I., O’Brien, John T., Rowe, James B.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283163/
https://ncbi.nlm.nih.gov/pubmed/34133849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51407
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