Synaptic loss in primary tauopathies revealed by [(11)C]UCB-J positron emission tomography

BACKGROUND: Synaptic loss is a prominent and early feature of many neurodegenerative diseases. OBJECTIVES: We tested the hypothesis that synaptic density is reduced in the primary tauopathies of progressive supranuclear palsy (PSP-Richardson’s syndrome) and amyloid–negative corticobasal syndrome (CB...

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Gepubliceerd in:Mov Disord
Hoofdauteurs: Holland, Negin, Jones, P. Simon, Savulich, George, Wiggins, Julie K., Hong, Young T., Fryer, Tim D., Manavaki, Roido, Sephton, Selena Milicevic, Boros, Istvan, Malpetti, Maura, Hezemans, Frank H., Aigbirhio, Franklin I., Coles, Jonathan P., O’Brien, John, Rowe, James B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611123/
https://ncbi.nlm.nih.gov/pubmed/32652635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28188
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