Synaptic loss in primary tauopathies revealed by [(11)C]UCB-J positron emission tomography

BACKGROUND: Synaptic loss is a prominent and early feature of many neurodegenerative diseases. OBJECTIVES: We tested the hypothesis that synaptic density is reduced in the primary tauopathies of progressive supranuclear palsy (PSP-Richardson’s syndrome) and amyloid–negative corticobasal syndrome (CB...

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Détails bibliographiques
Publié dans:Mov Disord
Auteurs principaux: Holland, Negin, Jones, P. Simon, Savulich, George, Wiggins, Julie K., Hong, Young T., Fryer, Tim D., Manavaki, Roido, Sephton, Selena Milicevic, Boros, Istvan, Malpetti, Maura, Hezemans, Frank H., Aigbirhio, Franklin I., Coles, Jonathan P., O’Brien, John, Rowe, James B.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611123/
https://ncbi.nlm.nih.gov/pubmed/32652635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28188
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