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Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits

Doxorubicin (Dox) is a chemotherapeutic agent used widely to treat a variety of malignant cancers. However, Dox chemotherapy is associated with several adverse effects, including “chemobrain,” the observation that cancer patients exhibit through learning and memory difficulties extending even beyond...

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Bibliografski detalji
Izdano u:Heliyon
Glavni autori: Alhowail, Ahmad H., Pinky, Priyanka D., Eggert, Matthew, Bloemer, Jenna, Woodie, Lauren N., Buabeid, Manal A., Bhattacharya, Subhrajit, Jasper, Shanese L., Bhattacharya, Dwipayan, Dhanasekaran, Muralikrishnan, Escobar, Martha, Arnold, Robert D., Suppiramaniam, Vishnu
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282984/
https://ncbi.nlm.nih.gov/pubmed/34296005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e07456
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