Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits

Doxorubicin (Dox) is a chemotherapeutic agent used widely to treat a variety of malignant cancers. However, Dox chemotherapy is associated with several adverse effects, including “chemobrain,” the observation that cancer patients exhibit through learning and memory difficulties extending even beyond...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Alhowail, Ahmad H., Pinky, Priyanka D., Eggert, Matthew, Bloemer, Jenna, Woodie, Lauren N., Buabeid, Manal A., Bhattacharya, Subhrajit, Jasper, Shanese L., Bhattacharya, Dwipayan, Dhanasekaran, Muralikrishnan, Escobar, Martha, Arnold, Robert D., Suppiramaniam, Vishnu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282984/
https://ncbi.nlm.nih.gov/pubmed/34296005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e07456
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