Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD(+)

Neuroinflammation is initiated by activation of the brain’s innate immune system in response to an inflammatory challenge. Insufficient control of neuroinflammation leads to enhanced or prolonged pathology in various neurological conditions including multiple sclerosis and Alzheimer’s disease. Nicot...

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Bibliografiske detaljer
Udgivet i:	J Neurochem
Main Authors:	Roboon, Jureepon, Hattori, Tsuyoshi, Ishii, Hiroshi, Takarada-Iemata, Mika, Nguyen, Dinh Thi, Heer, Collin D., O’Meally, Denis, Brenner, Charles, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Higashida, Haruhiro, Hori, Osamu
Format:	Artigo
Sprog:	Inglês
Udgivet:	2021
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8282715/ https://ncbi.nlm.nih.gov/pubmed/33871064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15367
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Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD(+)

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