Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate

le Cramer-Morales, Kimberly L., Heer, Collin D., Mapuskar, Kranti A., Domann, Frederick E.
Foilsithe in J Exp Pathol (Wilmington) (2020)

Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

le Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Foilsithe in bioRxiv (2020)

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

le Heer, Collin D., Sanderson, Daniel J., Voth, Lynden S., Alhammad, Yousef M.O., Schmidt, Mark S., Trammell, Samuel A.J., Perlman, Stanley, Cohen, Michael S., Fehr, Anthony R., Brenner, Charles
Foilsithe in J Biol Chem (2021)

Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD(+)

le Roboon, Jureepon, Hattori, Tsuyoshi, Ishii, Hiroshi, Takarada-Iemata, Mika, Nguyen, Dinh Thi, Heer, Collin D., O’Meally, Denis, Brenner, Charles, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Higashida, Haruhiro, Hori, Osamu
Foilsithe in J Neurochem (2021)

Superoxide Dismutase Mimetic GC4419 Enhances the Oxidation of Pharmacological Ascorbate and Its Anticancer Effects in an H(2)O(2)-Dependent Manner

le Heer, Collin D., Davis, Andrew B., Riffe, David B., Wagner, Brett A., Falls, Kelly C., Allen, Bryan G., Buettner, Garry R., Beardsley, Robert A., Riley, Dennis P., Spitz, Douglas R.
Foilsithe in Antioxidants (Basel) (2018)

Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide

le Sishc, Brock J., Ding, Lianghao, Nam, Taek-Keun, Heer, Collin D., Rodman, Samuel N., Schoenfeld, Joshua D., Fath, Melissa A., Saha, Debabrata, Pulliam, Casey F., Langen, Britta, Beardsley, Robert A., Riley, Dennis P., Keene, Jeffery L., Spitz, Douglas R., Story, Michael D.
Foilsithe in Sci Transl Med (2021)