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Intrahepatic Cholangiocarcinoma with Lymph Node Metastasis: Treatment-Related Outcomes and the Role of Tumor Genomics in Patient Selection

BACKGROUND: Lymph node metastasis (LNM) drastically reduces survival after resection of intrahepatic cholangiocarcinoma (IHC). Optimal treatment is ill-defined, and it is unclear if tumor mutational profiling can support treatment decisions. METHODS: Patients with liver-limited IHC with or without L...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Jolissaint, Joshua S., Soares, Kevin C., Seier, Kenneth P., Kundra, Ritika, Gönen, Mithat, Shin, Paul J., Boerner, Thomas, Sigel, Carlie, Madupuri, Ramyasree, Vakiani, Efsevia, Cercek, Andrea, Harding, James J., Kemeny, Nancy E., Connell, Louise C., Balachandran, Vinod P., D’Angelica, Michael I., Drebin, Jeffrey A., Kingham, T. Peter, Wei, Alice C., Jarnagin, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282702/
https://ncbi.nlm.nih.gov/pubmed/33963001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-21-0412
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