Distinct histomorphological features are associated with IDH1 Mutation in Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma has known histological heterogeneity. Mutations in IDH1 (mIDH1) define a molecular subclass of intrahepatic cholangiocarcinoma and IDH-targeted therapies are in development. Characterizing mIDH1 ICC histomorphology is of clinical interest for efficient identification....

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Udgivet i:Hum Pathol
Main Authors: Wang, Tao, Drill, Esther, Vakiani, Efsevia, Pak, Linda Ma, Boerner, Thomas, Askan, Gokce, Schvartzman, Juan Manuel, Simpson, Amber L., Jarnagin, William R., Sigel, Carlie S.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744317/
https://ncbi.nlm.nih.gov/pubmed/31121195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2019.05.002
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