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Systems biology informed neural networks (SBINN) predict response and novel combinations for PD-1 checkpoint blockade

Anti-PD-1 immunotherapy has recently shown tremendous success for the treatment of several aggressive cancers. However, variability and unpredictability in treatment outcome have been observed, and are thought to be driven by patient-specific biology and interactions of the patient’s immune system w...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Commun Biol
Asıl Yazarlar: Przedborski, Michelle, Smalley, Munisha, Thiyagarajan, Saravanan, Goldman, Aaron, Kohandel, Mohammad
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282606/
https://ncbi.nlm.nih.gov/pubmed/34267327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02393-7
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