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PrimPol‐mediated repriming facilitates replication traverse of DNA interstrand crosslinks
DNA interstrand crosslinks (ICLs) induced by endogenous aldehydes or chemotherapeutic agents interfere with essential processes such as replication and transcription. ICL recognition and repair by the Fanconi Anemia pathway require the formation of an X‐shaped DNA structure that may arise from conve...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8280817/ https://ncbi.nlm.nih.gov/pubmed/34128550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106355 |
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