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PrimPol‐mediated repriming facilitates replication traverse of DNA interstrand crosslinks
DNA interstrand crosslinks (ICLs) induced by endogenous aldehydes or chemotherapeutic agents interfere with essential processes such as replication and transcription. ICL recognition and repair by the Fanconi Anemia pathway require the formation of an X‐shaped DNA structure that may arise from conve...
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| 出版年: | EMBO J |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8280817/ https://ncbi.nlm.nih.gov/pubmed/34128550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106355 |
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