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Personalized Proteome: Comparing Proteogenomics and Open Variant Search Approaches for Single Amino Acid Variant Detection

[Image: see text] Discovery of variant peptides such as a single amino acid variant (SAAV) in shotgun proteomics data is essential for personalized proteomics. Both the resolution of shotgun proteomics methods and the search engines have improved dramatically, allowing for confident identification o...

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Détails bibliographiques
Publié dans:J Proteome Res
Auteurs principaux: Salz, Renee, Bouwmeester, Robbin, Gabriels, Ralf, Degroeve, Sven, Martens, Lennart, Volders, Pieter-Jan, ’t Hoen, Peter A.C.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2021
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280751/
https://ncbi.nlm.nih.gov/pubmed/33998808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.1c00264
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