Personalized Proteome: Comparing Proteogenomics and Open Variant Search Approaches for Single Amino Acid Variant Detection

[Image: see text] Discovery of variant peptides such as a single amino acid variant (SAAV) in shotgun proteomics data is essential for personalized proteomics. Both the resolution of shotgun proteomics methods and the search engines have improved dramatically, allowing for confident identification o...

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Publicado en:J Proteome Res
Autores principales: Salz, Renee, Bouwmeester, Robbin, Gabriels, Ralf, Degroeve, Sven, Martens, Lennart, Volders, Pieter-Jan, ’t Hoen, Peter A.C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2021
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280751/
https://ncbi.nlm.nih.gov/pubmed/33998808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.1c00264
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