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Personalized Proteome: Comparing Proteogenomics and Open Variant Search Approaches for Single Amino Acid Variant Detection

[Image: see text] Discovery of variant peptides such as a single amino acid variant (SAAV) in shotgun proteomics data is essential for personalized proteomics. Both the resolution of shotgun proteomics methods and the search engines have improved dramatically, allowing for confident identification o...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Salz, Renee, Bouwmeester, Robbin, Gabriels, Ralf, Degroeve, Sven, Martens, Lennart, Volders, Pieter-Jan, ’t Hoen, Peter A.C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280751/
https://ncbi.nlm.nih.gov/pubmed/33998808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.1c00264
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