A Novel Encochleated Formulation Improves Atovaquone Activity in a Murine Model of Pneumocystis Pneumonia

Although atovaquone is effective in treating and preventing Pneumocystis pneumonia (PCP), its use is limited by nonlinear absorption and adverse events. The current study was undertaken to examine the activity of encochleated atovaquone (eATQ), a novel lipid-crystal nanoparticle formulation, in a mo...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Cushion, Melanie T, Kumar, Parag, Lu, Ruying, Ashbaugh, Alan, Adeojo, Lilian W, Alfaro, Raul, Mannino, Raphael, Tramont, Edmund, Kovacs, Joseph A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280485/
https://ncbi.nlm.nih.gov/pubmed/33245345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa731
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