A Novel Encochleated Formulation Improves Atovaquone Activity in a Murine Model of Pneumocystis Pneumonia

Although atovaquone is effective in treating and preventing Pneumocystis pneumonia (PCP), its use is limited by nonlinear absorption and adverse events. The current study was undertaken to examine the activity of encochleated atovaquone (eATQ), a novel lipid-crystal nanoparticle formulation, in a mo...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Cushion, Melanie T, Kumar, Parag, Lu, Ruying, Ashbaugh, Alan, Adeojo, Lilian W, Alfaro, Raul, Mannino, Raphael, Tramont, Edmund, Kovacs, Joseph A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280485/
https://ncbi.nlm.nih.gov/pubmed/33245345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa731
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