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Effects of Atovaquone and Diospyrin-Based Drugs on the Cellular ATP of Pneumocystis carinii f. sp. carinii

Atovaquone (also called Mepron, or 566C80) is a napthoquinone used for the treatment of infections caused by pathogens such as Plasmodium spp. and Pneumocystis carinii. The mechanism of action against the malarial parasite is the inhibition of dihydroorotate dehydrogenase (DHOD), a consequence of bl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cushion, Melanie T., Collins, Margaret, Hazra, Banasri, Kaneshiro, Edna S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89752/
https://ncbi.nlm.nih.gov/pubmed/10681344
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