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Effects of Atovaquone and Diospyrin-Based Drugs on the Cellular ATP of Pneumocystis carinii f. sp. carinii

Atovaquone (also called Mepron, or 566C80) is a napthoquinone used for the treatment of infections caused by pathogens such as Plasmodium spp. and Pneumocystis carinii. The mechanism of action against the malarial parasite is the inhibition of dihydroorotate dehydrogenase (DHOD), a consequence of bl...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Cushion, Melanie T., Collins, Margaret, Hazra, Banasri, Kaneshiro, Edna S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.713-719.2000
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