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A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes
Successful cell division relies on the timely removal of key cell cycle proteins such as securin. Securin inhibits separase, which cleaves the cohesin rings holding chromosomes together. Securin must be depleted before anaphase to ensure chromosome segregation occurs with anaphase. Here we find that...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8280194/ https://ncbi.nlm.nih.gov/pubmed/34262048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24554-2 |
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