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Prometaphase APC(cdh1) activity prevents non-disjunction in mammalian oocytes
The first female meiotic division (MI) is uniquely prone to chromosome segregation errors through non-disjunction, resulting in trisomies and early pregnancy loss1. Here, we show a fundamental difference in the control of mammalian meiosis which may underlie such susceptibility. It involved a revers...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323444/ https://ncbi.nlm.nih.gov/pubmed/17891138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1640 |
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