The CRY box: a second APC(cdh1)-dependent degron in mammalian cdc20

Cdc20 and cdh1 are coactivators of the anaphase-promoting complex (APC). APC(cdc20) is necessary for the metaphase–anaphase transition and, at the end of mitosis, vertebrate cdc20 itself becomes a target for degradation through KEN-box-dependent APC(cdh1) activity. By studying the degradation of flu...

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Bibliographic Details
Main Authors: Reis, Alexandra, Levasseur, Mark, Chang, Heng-Yu, Elliott, David J, Jones, Keith T
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Scientific Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618383/
https://ncbi.nlm.nih.gov/pubmed/16878123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400772
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