The methyl donor S-adenosyl methionine reverses the DNA methylation signature of chronic neuropathic pain in mouse frontal cortex

Chronic pain is associated with persistent but reversible structural and functional changes in the prefrontal cortex (PFC). This stable yet malleable plasticity implicates epigenetic mechanisms, including DNA methylation, as a potential mediator of chronic pain–induced cortical pathology. We previou...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Pain Rep
Asıl Yazarlar: Topham, Lucas, Gregoire, Stephanie, Kang, HyungMo, Salmon-Divon, Mali, Lax, Elad, Millecamps, Magali, Szyf, Moshe, Stone, Laura
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wolters Kluwer 2021
Konular:
Basic Science
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280078/
https://ncbi.nlm.nih.gov/pubmed/34278163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PR9.0000000000000944
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