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S-adenosyl-methionine (SAM) alters the transcriptome and methylome and specifically blocks growth and invasiveness of liver cancer cells

S-adenosyl methionine (SAM) is a ubiquitous methyl donor that was reported to have chemo- protective activity against liver cancer, however the molecular footprint of SAM is unknown. We show here that SAM selectively inhibits growth, transformation and invasiveness of hepatocellular carcinoma cell l...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Wang, Yan, Sun, ZhongSheng, Szyf, Moshe
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762365/
https://ncbi.nlm.nih.gov/pubmed/29340097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22942
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