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Does positive MGMT methylation outbalance the limitation of subtotal resection in glioblastoma IDH-wildtype patients?

BACKGROUND: The impact on survival of complete resection (CR) in patients with malignant glioma and MGMT promoter methylation on adjuvant therapy strategies has been proven in the past. However, it is not known whether a MGMT promoter methylation can compensate a subtotal resection. Therefore, we an...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Mareike, Müller, Franziska, Staub-Bartelt, Julia, Ehrmann, Daniel, Hänggi, Michael, Sabel, Jörg, Felsberg, Marion, Rapp
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279995/
https://ncbi.nlm.nih.gov/pubmed/34185258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-021-03794-8
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