Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients

Methylation of the O(6)-Methylguanine-DNA methyltransferase (MGMT) promoter is predictive for treatment response in glioblastoma patients. However, precise predictive cutoff values to distinguish “MGMT methylated” from “MGMT unmethylated” patients remain highly debated in terms of pyrosequencing (PS...

Full description

Saved in:

Bibliographic Details
Published in:	Acta Neuropathol Commun
Main Authors:	Radke, Josefine, Koch, Arend, Pritsch, Fabienne, Schumann, Elisa, Misch, Martin, Hempt, Claudia, Lenz, Klaus, Löbel, Franziska, Paschereit, Fabienne, Heppner, Frank L., Vajkoczy, Peter, Koll, Randi, Onken, Julia
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2019
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6549362/ https://ncbi.nlm.nih.gov/pubmed/31167648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0745-z
Tags:	Add Tag No Tags, Be the first to tag this record!

Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients

Similar Items