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The Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between β(2)-Microglobulin and H Chain Conserved in Evolution

Cartilaginous fish are the most primitive extant species with MHC molecules. Using the nurse shark, the current study is, to the best of our knowledge, the first to present a peptide-loaded MHC class I (pMHC-I) structure for this class of animals. The overall structure was found to be similar betwee...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Wu, Yanan, Zhang, Nianzhi, Wei, Xiaohui, Lu, Shuangshuang, Li, Shen, Hashimoto, Keiichiro, Dijkstra, Johannes M., Xia, Chun
Format: Artigo
Idioma:Inglês
Publicat: AAI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278274/
https://ncbi.nlm.nih.gov/pubmed/34145057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2001165
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