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Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates
BACKGROUND: Classical major histocompatibility complex (MHC) class II molecules play an essential role in presenting peptide antigens to CD4(+) T lymphocytes in the acquired immune system. The non-classical class II DM molecule, HLA-DM in the case of humans, possesses critical function in assisting...
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| Publié dans: | BMC Evol Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4219347/ https://ncbi.nlm.nih.gov/pubmed/24279922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-260 |
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