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Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules

BACKGROUND: In sharks, chickens, rats, frogs, medaka and zebrafish there is haplotypic variation in MHC class I and closely linked genes involved in antigen processing, peptide translocation and peptide loading. At least in chicken, such MHCIa haplotypes of MHCIa, TAP2 and Tapasin are shown to influ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Evol Biol
1. Verfasser: Grimholt, Unni
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824609/
https://ncbi.nlm.nih.gov/pubmed/29471808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-018-1138-9
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