Synthesis of New 1H-1,2,3-Triazole Analogs in Aqueous Medium via “Click” Chemistry: A Novel Class of Potential Carbonic Anhydrase-II Inhibitors

A series of novel 1H-1,2,3-triazole analogs (9a–j) were synthesized via “Click” chemistry and Suzuki–Miyaura cross-coupling reaction in aqueous medium. The compounds were evaluated for their carbonic anhydrase-II enzyme inhibitory activity in vitro. The synthesis of triazole 7a was accomplished usin...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Avula, Satya Kumar, Khan, Majid, Halim, Sobia Ahsan, Khan, Ajmal, Al-Riyami, Samia Ahmed, Csuk, Rene, Das, Biswanath, Al-Harrasi, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278147/
https://ncbi.nlm.nih.gov/pubmed/34277561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.642614
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