RUFY4 exists as two translationally regulated isoforms, that localize to the mitochondrion in activated macrophages

We report here that RUFY4, a newly characterized member of the ‘RUN and FYVE domain-containing’ family of proteins previously associated with autophagy enhancement, is highly expressed in alveolar macrophages (AM). We show that RUFY4 interacts with mitochondria upon stimulation by microbial-associat...

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Vydáno v:R Soc Open Sci
Hlavní autoři: Valečka, Jan, Camosseto, Voahirana, McEwan, David G., Terawaki, Seigo, Liu, Zhuangzhuang, Strock, Eva, Almeida, Catarina R., Su, Bing, Dikic, Ivan, Liang, Yinming, Gatti, Evelina, Pierre, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2021
Témata:
Biochemistry, Cellular and Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278043/
https://ncbi.nlm.nih.gov/pubmed/34295519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.202333
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