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MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation
In response to Toll-like receptor ligands, dendritic cells (DCs) dramatically enhance their antigen presentation capacity by stabilizing at the cell-surface MHC II molecules. We demonstrate here that, in human monocyte-derived DCs, the RING-CH ubiquitin E3 ligase, membrane-associated RING-CH I (MARC...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2265198/ https://ncbi.nlm.nih.gov/pubmed/18305173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708874105 |
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