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A Sulfobetaine Zwitterionic Polymer-Drug Conjugate for Multivalent Paclitaxel and Gemcitabine Co-Delivery

A zwitterionic polymer-drug conjugate (ZPDC) strategy is developed for the co-delivery of paclitaxel (PTX) and gemcitabine (GEM) chemotherapeutics, as well as a near-infrared fluorescence imaging agent cyanine5.5 (Cy5.5). The well-defined ZPDC is synthesized by tandem azide-alkyne and thiol-ene clic...

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Detalhes bibliográficos
Publicado no:Biomater Sci
Main Authors: Sun, Haotian, Yan, Lingyue, Zhang, Runsheng, Lovell, Jonathan F., Wu, Yun, Cheng, Chong
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277739/
https://ncbi.nlm.nih.gov/pubmed/34105535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1bm00393c
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