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Variability within rare cell states enables multiple paths towards drug resistance

Molecular differences between individual cells can lead to dramatic differences in cell fate, such as death versus survival of cancer cells upon drug treatment. These originating differences remain largely hidden due to difficulties in determining precisely what variable molecular features lead to w...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Emert, Benjamin L., Cote, Christopher, Torre, Eduardo A., Dardani, Ian P., Jiang, Connie L., Jain, Naveen, Shaffer, Sydney M., Raj, Arjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277666/
https://ncbi.nlm.nih.gov/pubmed/33619394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-021-00837-3
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