Decreased K(ATP) Channel Activity Contributes to the Low Glucose Threshold for Insulin Secretion of Rat Neonatal Islets

Transitional hypoglycemia in normal newborns occurs in the first 3 days of life and has clinical features consistent with hyperinsulinism. We found a lower threshold for glucose-stimulated insulin secretion from freshly isolated embryonic day (E) 22 rat islets, which persisted into the first postnat...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Yang, Juxiang, Hammoud, Batoul, Li, Changhong, Ridler, Abigail, Yau, Daphne, Kim, Junil, Won, Kyoung-Jae, Stanley, Charles A, Hoshi, Toshinori, Stanescu, Diana E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276892/
https://ncbi.nlm.nih.gov/pubmed/34134142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqab121
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