Mechanisms of octanoic acid potentiation of insulin secretion in isolated islets

A potentiating effect of medium-chain triglycerides on glucose-stimulated insulin secretion (GSIS) has been observed since the 1960s. Subsequent observations identified octanoic acid (OA), the main component of medium-chain triglyceride, as the potentiator of GSIS, but the mechanism was unclear. We...

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Bibliographic Details
Published in:Islets
Main Authors: Zhang, Tingting, Chen, Pan, Stanley, Charles A., Hoshi, Toshinori, Li, Changhong
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682262/
https://ncbi.nlm.nih.gov/pubmed/30849280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2019.1566683
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