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Different Roles of TM5, TM6, and ECL3 in the Oligomerization and Function of Human ABCG2
ABCG2 is a member of the ATP-binding cassette transporter superfamily, and its overexpression causes multidrug resistance (MDR) in cancer chemotherapy. ABCG2 may also protect cancer stem cells by extruding cytotoxic materials. ABCG2 has previously been shown to exist as a high-order homo-oligomer co...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8276268/ https://ncbi.nlm.nih.gov/pubmed/22497316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300301a |
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