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Role of Transmembrane Segment 5 and Extracellular Loop 3 in the Homodimerization of Human ABCC1

Resistance to multiple anticancer agents is a major obstacle in the successful treatment of cancers. Overexpression of some ATP-binding cassette (ABC) membrane transporters such as ABCC1 has been shown to be a major contributor of multidrug resistance (MDR) in both laboratory cell line models and th...

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Detalhes bibliográficos
Main Authors: Yang, Youyun, Mo, Wei, Zhang, Jian-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095655/
https://ncbi.nlm.nih.gov/pubmed/21090806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101350x
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