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Predicting mechanism of action of novel compounds using compound structure and transcriptomic signature coembedding
MOTIVATION: Identifying mechanism of actions (MoA) of novel compounds is crucial in drug discovery. Careful understanding of MoA can avoid potential side effects of drug candidates. Efforts have been made to identify MoA using the transcriptomic signatures induced by compounds. However, these approa...
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| Publicat a: | Bioinformatics |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8275331/ https://ncbi.nlm.nih.gov/pubmed/34252937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btab275 |
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