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Predicting mechanism of action of cellular perturbations with pathway activity signatures
MOTIVATION: Misregulation of signaling pathway activity is etiologic for many human diseases, and modulating activity of signaling pathways is often the preferred therapeutic strategy. Understanding the mechanism of action (MOA) of bioactive chemicals in terms of targeted signaling pathways is the e...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7751003/ https://ncbi.nlm.nih.gov/pubmed/32653926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa590 |
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