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Within-Host Phenotypic Evolution and the Population-Level Control of Chronic Viral Infections by Treatment and Prophylaxis

Chronic viral infections can persist for decades spanning thousands of viral generations, leading to a highly diverse population of viruses with its own complex evolutionary history. We propose an expandable mathematical framework for understanding how the emergence of genetic and phenotypic diversi...

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Detalhes bibliográficos
Publicado no:Mathematics (Basel)
Main Authors: Gromov, Dmitry, Romero-Severson, Ethan O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274820/
https://ncbi.nlm.nih.gov/pubmed/34258245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/math8091500
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