Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer

The five-year survival rate for metastatic pancreatic cancer is currently only 3%, which increases to 13% with local invasion only and to 39% with localized disease at diagnosis. Here we evaluated repurposed mebendazole, an approved anthelminthic drug, to determine how mebendazole might work at the...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Williamson, Tara, de Abreu, Michelle Carvalho, Trembath, Dimitri G., Brayton, Cory, Kang, Byunghak, Mendes, Thais Biude, de Assumpção, Paulo Pimentel, Cerutti, Janete M., Riggins, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274724/
https://ncbi.nlm.nih.gov/pubmed/34262644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.28014
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