Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis

Autophagy inhibitors are currently being evaluated in clinical trials for the treatment of diverse cancers, largely due to their ability to impede tumor cell survival and metabolic adaptation. More recently, there is growing interest in whether and how modulating autophagy in the host stroma influen...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Rudnick, Jenny A., Monkkonen, Teresa, Mar, Florie A., Barnes, James M., Starobinets, Hanna, Goldsmith, Juliet, Roy, Srirupa, Bustamante Eguiguren, Sofía, Weaver, Valerie M., Debnath, Jayanta
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247603/
https://ncbi.nlm.nih.gov/pubmed/34168038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.345629.120
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